Two cars collided at on 1120 BST on Friday at Quarry Corner on the Kempstones Road.
The woman who expired was driving one of the cars and was on her own. Her name has not been released so far.
There were four people in another car; they were receiving to the Ulster Hospital, Dundonald. Three were as discharged, one woman is in hospital.
She is being kept overnight for surveillance.
The road has reopened after being closed for numerous hours after the crash.
Police have appealed for anyone who eye witnessed the accident to get in contact with them.
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